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Written by: Tricia Cook MEd, RSP, AOG, Montessorian
Emotional Intensity Advocate/Neurodiversity Resilience & Family Coach/Consultant, Online Tutor, Podcaster/Author & Developer of My ELBERT, owner and operator of…155 articles
July 23, 2023
BODY
Researchers found that the aging process in organisms can be influenced by the loss of epigenetic information, even without changes in the genetic code. In mice, the breakdown of epigenetic information leads to aging, but intriguingly, restoring the integrity of the epigenome can reverse the signs of aging.
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Recent research has discovered a connection between the epigenetic marking of the ‘satiety gene’ and the likelihood of obesity in women. The study found that women with a higher number of methyl groups on the POMC gene had a 44% increased risk of obesity.
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Recent research provides further evidence supporting the idea that exercise promotes youthfulness. The study reveals that exercise has a positive epigenetic effect on aging organisms, contributing to a more youthful state.
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A twin study reveals a compelling link between exercise and beneficial epigenetic changes. Twins who engaged in higher levels of physical activity exhibited fewer signs of metabolic disease and had lower epigenetic markers associated with a decreased risk of metabolic syndrome. These findings indicate that metabolic diseases are significantly influenced by an individual’s interaction with their environment rather than solely being determined by their inherited genetics.
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Another study recommended weekly levels of moderate-to-vigorous physical activity (MVPA) and engaged in weight training once or twice a week experienced a 41-47% lower risk of death compared to those who were physically inactive.
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Based on the information presented in the study titled “Cntnap2-dependent molecular networks in autism spectrum disorder revealed through an integrative multi-omics analysis” published in Molecular Psychiatry (nature.com), it appears that CNTNAP2 dysfunction is a significant factor in autism spectrum disorder (ASD).
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Obesity might be considered a neurodevelopmental disorder, as it is influenced by the epigenetic development in the arcuate nucleus of the hypothalamus. The research findings indicate that developmental epigenetics plays a crucial role in how both environmental and genetic factors contribute to the risk of obesity.
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Post-mortem analysis of the brains of individuals with Parkinson’s disease unveiled over 200 genes with distinct epigenetic markers in comparison to healthy brains. However, the genes impacted were notably different between women and men, suggesting that epigenetic changes linked to Parkinson’s disease vary significantly based on gender.
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Researchers study epigenetic aging to gain insights into the biological aging process and to identify potential biomarkers or therapeutic targets for age-related diseases. Research shows that accelerated biological and epigenetic aging are linked to lower odds of older women reaching the age of 90 and beyond. This suggests that biological age could serve as a crucial factor in determining one’s potential for living a longer and healthier life. Therefore, instead of relying on birthdate, biological age emerges as a more significant indicator of healthy longevity.
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MIND
This study has discovered dysregulation of stress genes in children after experiencing injuries from abuse, as opposed to accidental injuries. The research reports on epigenetic changes to the FKBP5 gene, a crucial gene involved in regulating the body’s stress response.
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This research highlights the potential significance of early-life experiences in shaping future health outcomes and opens new avenues for understanding and addressing long-term health risks stemming from childhood trauma. Epigenetic markers associated with childhood trauma can serve as biomarkers, helping predict the risk of various issues, including addiction, depression, and both physical and mental health problems, even after a span of 17 years.
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Similarly, these findings underscore the critical impact of early-life experiences on mental health outcomes and emphasize the importance of addressing childhood trauma to reduce the risk of long-term mental health challenges.
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For researchers the question arises whether misfolded proteins play a role as a catalyst in the development of neurodevelopmental and psychiatric diseases. Individuals with schizophrenia exhibit a noteworthy increase in tandem repeats in their genome, up to 7% more compared to those without this mental health disorder. The identified genes affected by these tandem repeats are essential for synaptic and neuronal signaling functions.
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Researchers are focusing on the nucleus to gain insights into the development of amyloid and find potential ways to halt its formation. However, it would be highly beneficial to have more research that takes a broader perspective and examines external factors, such as epigenetics, including diet and lifestyle.
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Researchers observed changes in gene expression in offspring and even grand-offspring by altering the epigenetic markers on chromosomes. These findings demonstrate the transmission of epigenetic memory across multiple generations.
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This study employed three distinct animal models to examine nearly 30,000 genes, revealing a correlation between Alcohol Use Disorders (AUDs) and specific groups of genes that influence neuronal plasticity and pain perceptions.
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SPIRIT
Spiritual epigenetics is a fascinating concept that explores the interplay between spirituality and genetics, revealing how one’s faith and beliefs can influence gene expression and overall well-being.
Lastly, researchers need to explore this fascinating revelation, it may provide new insights into how individuals can improve their well-being and lead healthier, more fulfilling lives through the power of faith and spirituality.
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The Spirit of Love is primarily focused on the spiritual and relational aspect of God’s love and its impact on our lives as believers. It highlights the role of the Holy Spirit in revealing the depth of God’s love and selfless sacrifice for humanity through Jesus Christ.
As we delve into the spiritual significance of the “4th dimension,” we find ourselves immersed in the eternal and boundless love of God, echoing throughout time and eternity.
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As believers seek a deeper understanding of the Holy Spirit and His work in their lives, they can draw from the richness of these various aspects to experience a more profound and transformative relationship with God.
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Through hope and prayer, the Spirit grants wisdom and revelation, enlightening believers’ hearts and leading them to a deeper understanding of God’s calling and purposes.
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The human brain, while a miraculous creation, can only offer limited insights into the divine nature and the mysteries of God. As well, the integration of these brain regions and spiritual attributes in spiritual epigenetics can lead to more informed, thoughtful, and meaningful life decisions.
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Dysregulation of epigenetic processes can contribute to the development of diseases such as cancer, autoimmune disorders, and neurological conditions. Moreover, epigenetic modifications are influenced by environmental factors, including diet, stress, and exposure to toxins, highlighting the interplay between genetics and the environment in shaping an individual’s health and susceptibility to diseases.
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Metaepigenetics
The genome of an organism comprises its chromosomal genes and additional genetic information found in other organelles or endosymbionts, such as plasmids, chloroplasts, and mitochondria. Similarly, the microbiome refers to all the genes present in the microorganisms that inhabit a specific host. The microbiome is also known as the metagenome.
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A comprehensive analysis found notable distinctions in gut bacteria between healthy individuals and those with preclinical Alzheimer’s disease, despite their similar diets. The variations involved the types of bacteria present and the biological processes they engage in. Interestingly, these differences were associated with levels of amyloid and tau, which increase before cognitive symptoms manifest.
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The researchers conducted an investigation into the gut microbiomes of the study participants. They employed 16S rRNA gene sequencing to detect and analyze the bacteria present in the stool samples. Additionally, the findings of the study propose that manipulating the gut microbiome could be a promising strategy to improve cognitive function in individuals with mild cognitive impairment.
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Metaepigenetics is a field of study that explores the interaction between genetics and the environment in shaping an organism’s traits and behavior.
Epigenetic and metaepigenetic research can help us to better understand mental health disorders and develop new treatments.
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When considering artifacts, symbols, and the Word (referring to religious texts like the Bible), we can view how cultural and environmental factors have influenced the creation, preservation, and interpretation of these historical objects and sacred scriptures.
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The studies published in Nature Neuroscience in 2022 and Molecular Psychiatry in 2021 offer intriguing insights into the emerging field of metaepigenetics, exploring the link between early-life stress, DNA methylation, and behavior in mice. These findings have significant implications for understanding the complex interplay between our environment, genetic regulation, and subsequent behavioral outcomes.
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Researchers have found communication within the immune system is essential for the brain to alert the body about potential environmental dangers and prompt avoidance of threats. The ability of allergen-specific IgE and mast cells to promote avoidance relies on cysteinyl leukotrienes and growth and differentiation factor 15 (GDF15). Additionally, the research indicates that genetic background, as observed in C57BL/6 and BALB/c mouse strains, significantly influences avoidance behavior.
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“The thymus plays a significant role in supporting and maintaining the body’s overall health and well-being by producing and regulating these immune cells.”
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Metaepigenetic memory is a newer concept in epigenetics, and it refers to the ability of cells to remember and transmit information about their environment to future generations.
As believers immerse themselves in prayer, biblical contemplation, and the study of God’s word, their spiritual DNA is imprinted with divine wisdom and insight, allowing them to comprehend the hidden depths of God’s message.
Read More Here: https://www.youtube.com/watch?v=Wa-DsykrPt0; https://www.linkedin.com/pulse/epigenetics-body-mind-spirit-where-everyone-learns-x-tricia-cook
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Status is onlineTricia Cook MEd, RSP, AOG, MontessorianEmotional Intensity Advocate/Neurodiversity Resilience & Family Coach/Consultant, Online Tutor, Podcaster/Author & Developer of My ELBERT, owner and operator of…Published • 1w155 articles#epigenetics#genetics#health#dna#biology#science#cellbiology#epigenetica#freedom#higherconsciousness#physics#healing#love#love#hope#selfcare#mentalhealth
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