Delight (mind-RAS-Gut): Strength, Might, Simple (Affirmation (Blessing of Thanksgiving): -Abound-Heart/Spirit, Justifying Faith-justice)
RAS – “The Door” Rectangular Activation System
The RAS being activated via the pons, and thymus leads someone to a “Flexible Mind”. This flexible mind is due to the transference of “cells” and activating the synapse of the neurons to increase neuroplasticity. A “Ridged Mind” is a closed mind-remember, if you don’t use an “open mind”, you lose adaptability (placidity-that is, also read below abstract thinking). -Tricia Cook
14 – 2.3 RAS Rectangular Activation System Note: includes Soma and Alta Major Chakras illustration
Vagus Nerve & RAS Vibrating Alta Major Chakra (*aka God Awareness Chakra)
The Reticular Activating System (RAS)- Ras/ HPA & ACC/Gut – to know, perceive, recognize, have, aware, cognizant, do laugh, reverence, ask, repent, reconciliation which is a network of neurons (hyper-, hypo-, or, varied) located in the brain stem that project anteriorly to the hypothalmus to mediate behavior such as sleep, memory, and learning; as well as, both posteriorly to the and directly to the cortex for activation of awake, desynchronized cortical EEG patterns. The reticular formation (part of pons-see below) is a set of interconnected nuclei that are located throughout the brain stem. It is not anatomically well-defined, because it includes neurons located in different parts of the brain. The neurons of the reticular formation make up a complex set of networks in the core of the brain stem that extend from the upper part of the midbrain to the lower part of the medulla oblongata. The reticular formation includes ascending pathways to the cortex in the ascending reticular activating system and descending pathways to the spinal cord via the reticulospinal tracts. [2] It is holistically and spiritually known from being a center “where we can create our own reality” whether positive, negative, or neutral. Knowing: What we focus on in our mind (thymus), pons (dream center) then comes to fruition here in our RAS. The reticular activating system’s fundamental role is regulating arousal and sleep−wake transitions. The ascending projections of the reticular activating system enhance the attentive state of the cortex and facilitate conscious perception of sensory stimuli. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013218/; https://commons.wikimedia.org/wiki/File:Gray701.png; https://en.wikipedia.org/wiki/Reticular_formation].
Targeting these cells, as reported in the journal #Nature Neuroscience, modulated memory retrieval and altered anxiety-like behaviors in mice. Essentially, the #UNC scientists boosted the electrical activity between cells in the hypothalamus and the hippocampus to create new neurons – an important process called neurogenesis “Targeting the hypothalamic neurons to enhance adult hippocampal neurogenesis will not only benefit brain functions,” said senior author @Juan Song, PhD, associate professor of pharmacology, “but also holds the potential to treat cognitive and affective deficits associated with various brain disorders.” [Retrieved from https://neurosciencenews.com/optogenetics-neurogenesis-20603/].
Note: the thalamus has been found to be less passive in cognitive functions may indeed be supported by a more general role in shaping mental representations. Several features of thalamocortical circuits are consistent with this suggested role, and we highlight how divergent and convergent thalamocortical and corticothalamic pathways may complement each other to support these functions. Furthermore, the role of the thalamus for subcortical integration is highlighted as a key mechanism for maintaining and updating representations. [Retrieved from https://www.jneurosci.org/content/39/1/3?fbclid=IwAR1mUDSUOD3kolCFIoVRTXf6rsLZ6nbZfnMI8oRUEgwZ37EI8ppd3USLD2s]. Columbia University research, studied cognitive abnormalities associated with schizophrenia may be traced to altered activity in the thalamus during adolescence. The researchers have reported new evidence that cognitive abnormalities seen in neuropsychiatric disorders such as schizophrenia may be traceable to altered activity in the thalamus during adolescence, a time window of heightened vulnerability for schizophrenia. [Retrieved from https://neurosciencenews.com/thalamus-activity-schizophrenia-20641/].
The ACC (see top)- is part of RAS (Pineal Gland, Pituitary Gland) associated with the alta major chakra and shame.
HPA (see top)-(Hypothalamic–Pituitary–Adrenal Axis) associated with the soma chakra and anger.
Both are associated with the thymus chakra aka vagus nerve chakra.
Note: Important RAS info. includes the following excerpt… ‘The RAS is said to be the gas pedal [slow (hypo-), accelerate (hyper-) or varied cognitive speed processing] that ignites the diencephalon (the hypothalamus and thalamus) as well as the cortical areas [where all long-term memory/storage takes place] of the brain’ (Petty 1996). https://nlpca.com/creating-an-optimal-future-for-yourself/
Daniel Kahneman is correct, engaging the reader in a lively conversation about how we think, reveals where we can and cannot trust our intuitions and how we can tap into the benefits of slow thinking [hypo-; as well hyper-, varied speed processing]. [Retrieved from https://suebehaviouraldesign.com/about-us/contact/See]
Images Below: Left- hyper speed processing, Right- hypo- speed processing (then vice versa)
15 – Left- hyper speed processing, Right- hypo- speed processing
16 – Right- hyper speed processing, Left- hypo- speed processing
“Cognitive flexibility is related to our perceptions, emotions, actions and even our deep motivations. A change in environment, attitude, or behavior will also influence the way we think. … When we are able to make a mental shift without remaining stuck in a particular mindset, we’re practicing mental flexibility.” [Retrieved from https://www.prospectmedical.com/resources/wellness-center/mental-flexibility].
“We all have what is needed for “elastic thinking”—to a greater extent, perhaps, than we realize. It’s just a matter of recognizing the needed skills, Mlodinow argues, and nurturing them. He answered questions from Mind Matters editor Gareth Cook. “[Retrieved from https://www.scientificamerican.com/article/the-power-of-flexible-thinking/].
“Fix these words of mine in your hearts and minds; tie them as symbols on your hands and bind them on your foreheads.” Deuteronomy 6:8
The GUT- The SECOND Brain & Solar Plexus
The gut consist of 75% of our immune system, and the microbiome refers to the collective genomes of the micro-organisms in a particular environment, and microbiota is the community of micro-organisms themselves (box 1). Approximately 100 trillion micro-organisms (most of them bacteria, but also viruses, fungi, and protozoa) exist in the human gastrointestinal tract12—the microbiome is now best thought of as a virtual organ of the body. The human genome consists of about 23 000 genes, whereas the microbiome encodes over three million genes producing thousands of metabolites, which replace many of the functions of the host,13 consequently influencing the host’s fitness, phenotype, and health.2
The human body is composed of a complex biological system; with over 90% of microbiota cells and 10 million microbiota genes (1), it possesses over 100 trillion bacteria, 10 times the number of human body cells, 150 times the number of human genes, 1,000 species and over 7,000 strains (2). [Retrieved from https://www.frontiersin.org/articles/10.3389/fpsyt.2018.00223/full].
- Microbiome—the collective genomes of the microorganisms in a particular environment
- Microbiota—the community of microorganisms themselves
- Microbiota diversity—a measure of how many species and, dependent on the diverse indices, how evenly distributed they are in the community. Lower diversity is considered a marker of dysbiosis (microbial imbalance) in the gut and has been found in autoimmune diseases and obesity and cardio metabolic conditions, as well a in elderly people.
- Colonocytes—epithelial cells of the colon
According to several studies, there is considerable evidence showing that the gut microbiome not only affects the digestive, metabolic, and immune functions of the host but also regulates host sleep and mental states through the microbiome-gut-brain axis. Preliminary evidence indicates that microorganisms and circadian genes can interact with each other. The characteristics of the gastrointestinal microbiome and metabolism are related to the host’s sleep and circadian rhythm. Moreover, emotion and physiological stress can also affect the composition of the gut microorganisms. The gut microbiome and inflammation may be linked to sleep loss, circadian misalignment, affective disorders, and metabolic disease. [Retrieved from https://www.frontiersin.org/articles/10.3389/fpsyt.2018.00669/full].
Stress also exerts a great influence on the functions of our immune system: if the immune system is somehow compromised and cannot properly cope with physicochemical stresses [such as food/nutrition, noise, pollution, metabolic disorder, infection, and inflammation], or if the stress exceeds the regular adaptability of the immune system, this leads to diseased states that may develop into fatal conditions. [Retrieved from https://www.frontiersin.org/research-topics/5755/stress-and-immunity].
LEARN More: Ancient grains in their “whole grain” form provide fibre, vitamins and minerals, healthy fats (listed HERE); especially farro is particularly high in protein and fiber, which may help maintain a healthy body weight by curbing your appetite and keeping you full after meals. Farro is also high in antioxidants like polyphenols, carotenoids, and phytosterols, which may lower your risk of several chronic illnesses, such as heart disease and certain cancer (31Trusted Source, 32Trusted Source). Research shows that people who eat more whole grains may have a lower risk of heart disease, stroke, diabetes, and some cancers- plus PCH other natural way of “Promot[ing] Overall Digestive Health” along with “Help[ing] Defend Against Occasional Constipation, Diarrhea, Gas and Bloating.”
17 – Retrieved from https://riteboost.com/dashboard/
See cell health above [Retrieved from Inflammation and Repair in Inflammatory Bowel Disease: Clinical, Translational and Experimental Studies https://www.frontiersin.org/research-topics/27082; https://www.bmj.com/content/361/bmj.k2179}
The enteric nervous system (ENS) is a large division of the peripheral nervous system (PNS) that can control gastrointestinal behavior independently of central nervous system (CNS) input. Mammalian neurons are located in either the CNS (brain and spinal cord) or PNS (cells with SOMA outside the brainleft and spinal cord). Retrieved from https://neurosciencenews-com.cdn.ampproject.org/c/s/neurosciencenews.com/ent-gut-second-brain-19393/amp/
NOTE: The Soma and Ras (see epigenetics and learning disabilities above) cells regulate bodily processes. Therefore, needing neutrality, balance, equality of the thymus for cells to function with cytoskeleton integrity, cell proliferation, cell differentiation, cell adhesion, apoptosis, and cell migration (Read About RAS, soma, alta major chakras (energy centers-wheels) and cerebral cortex above).
Bliss (heart-pons): Joy, Power, Complete (Intent (Praise of Trust):-Arise-Mind/Soul, Indwelling Faith-Love)
Pons- “The Gate” parts of the brain- I describe as heart not mind for that would be the RAS/Gut, and the thymus is the “Leb” which is heart/mind
18 – image 4.1 Pons Illustration works with RAS (*aka God Awareness Chakra)
19 – [nucleus accumbens. Retrieved from https://neuroscientificallychallenged.com/posts/know-your-brain-nucleus accumbens?fbclid=IwAR0ZYZEI0EBz6_VtZ4deghU1BeclAbJcKO3xZkmUq9zbYifNUHI45P338FA]
The pons is part of the brainstem that in humans and other bipeds lies inferior to the midbrain, superior to the medulla oblongata and anterior to the cerebellum. [1] The pons integrates both the medulla oblongata and the thalamus (NOTE: the importance of conscious reappraisal of emotions (emotional reappraisal) such as shame/empathy and anger/strength for the ARAS). In the thalamus, students can have a slow (hypo-), accelerated (hyper-) or varied processing, and they have a problem with sensory integration disorders (corollary discharge) and emotional intensity or insensitivity with their neurodifference. The Pons, like the RAS, is responsible for arousal (hyper-, hypo- and varied). Plus, the pons connects areas of the brain that controls autonomic functions (parasympathetic (shame) /sympathetic (anger)): Acting or occurring involuntarily, without conscious control, in the somatic nervous system such as sleep and histamine inhibitors: The part of the peripheral nervous system that transmits signals from the central nervous system to skeletal muscles, and from receptors of external stimuli such as mediating sight, hearing, and touch and movement including speaking with conscious control (RAS-alta major chakra, crown chakra specifically via the thymus (Vagus Nerve Chakra) [Retrieved from https://en.wikipedia.org/wiki/Pons].
Ventral Tegmental Area (VTA)
The pons controls our breath known as ‘life’. God gave us the ‘life’, so we can be the breath of God, leading a pure and blameless life. The pons just doesn’t serve to help the different lobes communicate, but also is the veil of God. The pons area also contains the trapezoid body (RAS) where you are able to vocalize sounds. This allows us to sing, praise and speak, and share His word- Hallelujah and Gregorian Chants and Turning Hatred/Grief into Joy: Ut Queant Laxis HERE. Note: from the (2016) study…higher-frequency LFP oscillation (CFC) is enhanced in the human brain during high attentional demand, and has been linked to cognitive tasks not only in cortical brain regions, but also in deep limbic structures, such as the amygdala, hippocampus, and nucleus accumbens. SEE hippocampus and olfactory sense below (Retrieved from https://www.jneurosci.org/content/36/49; (Szczepanski et al., 2014);/12448?fbclid=IwAR0gqnyZ9b_0_ViS_yIa0186bY8Wkax6eZ_joF2fxTGLZqe8ZR5yO_pIvuI.; Structure and Function of the Brain | Boundless Psychology, https://courses.lumenlearning.com).
An interesting study recently has found: Volume decreases in cortical areas, the amygdala, and basal forebrain in Parkinson’s patients correlated with worsening symptoms of the disease. A team of researchers from Forschungszentrum Jülich, Heinrich-Heine-University Düsseldorf and Ernst-von-Bergmann Klinikum Potsdam analyzed the changes of brain volumes in 37 Parkinson’s patients and 27 controls at up to 15 time points over up to 8.8 years using magnetic resonance imaging (MRI). Previous in vivo studies had either measured brain volumes in Parkinson’s patients only at fewer time points or over shorter periods. [Retrieved from https://neurosciencenews.com/parkinsons-brain-volume-20610/?].
“All Scripture is God-breathed and is useful for teaching, rebuking, correcting and training in righteousness,..” https://www.bible.com/en-GB/bible/111/2TI.3.16.NIV
People also ask: What is the pons in the limbic system? Role of the pons in the carotid sympathetic chemoreflex?
Carotid Body- The carotid body is a chemoreceptor located in the adventitia of the bifurcation of the common carotid artery. Chemoreceptor function: Carotid body monitors the blood’s pH, pCO2, and pO2 and thereby modulates cardiovascular and respiratory function primarily through sympathetic tone. [Retrieved from https://medicine.uiowa.edu/iowaprotocols/carotid-body-and-carotid-sinus-general-information].
The carotid chemoreceptor (CC) controls your breathing during exercise, The mass discharges of the splanchnic sympathetic (SND) and phrenic nerves (PND) were recorded in urethananesthetized rats with resected vagal and aortic nerves. Carotid chemoreceptor (CC) stimulation with N2 inhalation (4-12 s) or cyanide (50-100 micrograms/kg iv) activated SND in bursts synchronized with the postinspiratory phase (mean SND increase: 105 +/- 8%), raised AP, and increased PND rate and amplitude (n = 40). Brain transection at superior collicular level produced no effect. The sympathetic (SChR) and respiratory chemoreflexes (RChR) were reduced after transections through the pons. Lesions of the dorsolateral pons (dl-pons) produced CO2-dependent apneusis and/or tachypnea at rest. [Retrieved from https://pubmed.ncbi.nlm.nih.gov/8067462/].
NDPs- “The cerebellar theory” (Nicolson, Fawcett, & Dean, 2001) states, with mixed empirical support, that poor automaticity and motor deficits in individuals with dyslexia may be associated with a dysfunction of the cerebellum (Feng et al., 2017; Vias & Dick, 2017). [Retrieved from https://onlinelibrary.wiley.com/doi/10.1002/dys.1681?fbclid=IwAR3pdYZTYwoFMSFASW8CDJwzOpyNRVpMyt38K0_K-4IweECeBJZIrNbmaSE].
The archipallium or primitive (“reptilian”) brain, comprising the structures of the brain stem – medulla, pons, cerebellum, mesencephalon, the oldest basal nuclei – the globus pallidus and the olfactory bulbs. The paleopallium or intermediate (“old mammalian”) brain, comprising the structures of the limbic system. Note: This is study on and exercise-induced changes in the DA-D2R in the dopamine-depleted basal ganglia are consistent with the potential role of this receptor in modulating medium spiny neurons (MSNs) function and behavioral recovery. The primary conclusion of our study is that exercise in the form of intensive treadmill running facilitates neuroplasticity through increased expression of striatal DA-D2Rs, a process most evident in the injured brain. [Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273304/] . Note: In my program, I emphasize yoga, tai chi,qigong type exercises when in the stage of recognition of soul and intents- which works on the cellular level! [Retrieved from Google Image Result for Https://Biologydictionary.net/Wp-Content/Uploads/2020/11/Pons.jpg</i>, images.app.goo.gl/THSvxHLckja1]
The level of dopamine in the brain may have an impact on emotional recognition in those with Parkinson’s disease and schizophrenia, a new study reports. Emotion recognition among people with disorders such as Parkinson’s disease or schizophrenia may be affected by changes in the levels of dopamine in the brain, say researchers at the University of Birmingham. Dopamine is a chemical messenger – often known as the ‘happy hormone’ – that carries signals controlling mental and emotional responses in the brain. Parkinson’s disease and other neurological disorders are known for their links with low or disrupted dopamine levels that cause those affected to struggle with a number of social skills. This is the first time, however, that a positive connection has been made between dopamine and the ability to recognize emotions in others. [Retrieved from https://neurosciencenews.com/dopamine-emotion-20648/].
As well, researchers have designed a new method of converting non-neural cells into functioning neurons that are able to form synapses, dispense dopamine, and restore the function of neurons undermined by Parkinson’s associated destruction of dopaminergic cells. [Retrieved from https://neurosciencenews.com/ipsc-dopamine-parkinsons-neurons-20568/]. As well, exercise even improves motor behavior in people with Parkinson’s disease, but the exact mechanism is not known. One possibility is through an increase in dopamine, a neurotransmitter needed for motor and emotional control that declines as the disease progresses. [Retrieved from https://neurosciencenews.com/exercise-dopamine-20592/].
Since the pons and the thymus (see below) as well as the RAS work together, Students with (anger) Sympathetic Functional System Dominance (SFD) can have problems “Seeing God” (God’s Energy- lucid dreams, “bind on forehead”) and “feeling worthy” to be called on by God (Aphantasia)- for God awareness they need circumstantial evidence or can go to extreme become ulta-religious constantly “breaking down” the Bible and religion or non-religious completely. Those with a (shame) Parasympathetic Functional System Dominance (PFD) have difficulties with reliance and resilience that’s “Hearing God” (God’s Essence- symbols, voice, “tie on hands”) and “feeling enough” to be chosen by God- for God awareness being calm in the mind- being present and ruminating on past/future a must. (PONS is addressed more in My ELBERT program: includes PYAM & RAS exercises body, breath, calm delight through Prayer, Yoga, Affirmation, and Meditation which connects us to God- see section below). Note: Students with Sympathetic Functional System Dominance (SFD) and Parasympathetic Functional System Dominance (PFD) have high allergy rates and sleep disturbances (see other complications below) which contains the Glia, also called glial cells or neuroglial, are non-neuronal cells in the central nervous system (brain and spinal cord) and the peripheral nervous system.
20 – 4.1b Peripheral Nervous System illustration
(peripheral sends info. to CNS- has effect on CNS as well as EM Field aka “the senses”)
21 – Image 4.1a Pons Axial illustration
Note: For those with Dysphonetic (auditory) and Dsyeidetic (visual-surface) Dyslexia, the medial longitudinal fasciculus of the pons carries information about the direction that the eyes should move. It connects the cranial nerve nuclei III (Oculomotor nerve), IV (Trochlear nerve) and VI (Abducens nerve) together, and integrates movements directed by the gaze centers (frontal eye field) and information about head movement (from cranial VIII, Vestibulocochlear nerve- which The vestibulocochlear nerve is unusual in that it primarily consists of bipolar neurons. It is the nerve responsible for the special senses of hearing (via the cochlear nerve), and balance (via the vestibular nerve). Then, the cochlea detects the magnitude and frequency of sound waves. Students with dyslexia have tendency for speech deficits and chronic ear infections, auditory as well as visual processing issues in the terms of being a sound and word processing disorder. Note: In some cases, it’s sometimes coordination, balance, and conflicting signals in the inner ear, eyes, and sensory receptors.
22 – Retrieved from https://epomedicine.com/medical-students/brodmann-areas-lesions/
Linguists are interested in language for its own sake, as a complex product of the human mind. They are also interested in how language develops in children, how it changes over time, and how it is used in human society. Furthermore, Neuroscientist Suzana Herculano-Houzel has pointed out that our brains are different because of the number of neurons packed into our skulls — it’s less about the size of our brains. The density of that packing, and the ensuing neuronal connections this density allows for, gives rise to our ability to acquire language from birth and use it till death. She assumes that the main function of the brain is to regulate our bodies as we move through life. That means that at every given moment, our brains assess our hunger, threat levels, etc. to figure out how much energy we need to get through the day. Thinking and cognitive perception are secondary products of how our brain responds predicatively to our environment. If the grammatical system is a resource that the brain uses depending on context, then our emotions and identity can also affect how we use grammar. This is precisely what we have found. [Retrieved from https://www.umass.edu/linguistics/; https://neurosciencenews-com.cdn.ampproject.org/c/s/neurosciencenews.com/emotion-grammar-linguistics-19790/amp/?fbclid=IwAR3Uu9_tlLeZS-7upnvBRvIbBvarR46E9SathZ7y3fKeLSoWBwQ8y4JZFnU].
In addition, these Brodmanns [see Ras and Pons above] have been widely redefined, discussed, debated, and refined exhaustively based on cytoarchitecture, cortical functions, and brain plasticity. Brodmann areas of the cerebral cortex are based on the types of neurons and connections that typically found each region. For Dyslexia this includes the left hemisphere language zones of their brain, (ie anatomic regions called Superior Temporal Gyrus, Angular Gyrus and Supramarginal gyrus, Broca’s region). There are 52 Brodmann regions, covering the primary somatosensory cortex, primary motor cortex, somatosensory association cortex, premotor and supplementary motor cortex, dorsolateral/anterior prefrontal cortex, anterior prefrontal cortex, and primary visual and audio cortexes, plus additional areas. BA18 of Brodmann (human) refers to a subdivision of the cytoarchitecturally defined occipital region of cerebral cortex. In the human it is located in parts of the cuneus, the lingual gyrus and the middle occipital gyrus of the occipital lobe. Brodmann area 22 is cytoarchitecturally located in the posterior superior temporal gyrus of the brain. In the left cerebral hemisphere, it is one portion of Wernicke’s area. The prefrontal cortex contains Brodmann areas is thought to be involved in psychological functions such as executive tasks, attention, and memory. This Research Topic, since they are the most rostral, and might be involved in more elementary computations as compared to, say, BA46, which is clearly involved in working memory. Also, Brodmann area 10 (BA10, frontopolar prefrontal cortex, rostrolateral prefrontal cortex, or anterior prefrontal cortex, the area is “described as “one of the least well-understood regions of the human brain”.[2] Ronel (2018) conducted a similar analysis for ADHD, in terms of 4 types of selection/inhibition (lateral BA 8 – motor selection/inhibition; lateral BA 9 – emotion selection/inhibition; lateral BA 10 – memory selection/inhibition; lateral BA 11 – sensory selection/inhibition). Present research suggests that it is involved in strategic processes in memory recall and various executive functions. During human evolution, the functions in this area resulted in its expansion relative to the rest of the brain.[3]” [Retrieved from https://www.kenhub.com/en/library/anatomy/brodmann-areas; https://www.frontiersin.org/articles/10.3389/fnbeh.2013.00198/full]
“Just as we live our life out of memory, thinking and dwelling in the past as a way of creating the future in the present by using the same idea to create a new variation, our body is regenerated and sustained out of the same memory. The mind forms an astral image as a hologram that imprints the etheric body with the information of that image.” [Retrieved from HERE; https://www.frontiersin.org/research-topics/19625/the-four-streams-of-the-prefrontal-cortex; http://ecotopia.org/thymos-as-biopsychological-metaphor-the-vital-root-of-consciousness/].
Happiness (heart mind- Thymus, heart/mind “the Leb”): Peace, Authority, Absolute (Revelation (Hope of Forgiveness): -Behold-Heart/Soul Saving Faith-peace)
Thymus- “The Second Gate”
23 – image 4.2 thymus illustration works with RAS illustration
(has an effect to peripheral, Vagus Nerve, CNS- as well as EM Field aka “the senses”)
‘T cells are critical to the adaptive immune system’: Stopping Inflamation and Even Damage
The collaboration between Professor Adrian Liston (Babraham Institute) and Professor Matthew Holt (VIB and KU Leuven; i3S-University of Porto) has produced a targeted delivery system for boosting the numbers of specialized anti-inflammatory immune cells specifically within the brain to restrict brain inflammation and damage. The research team found that regulatory T cell numbers were low in the brain because of a limited supply of the crucial survival molecule interleukin 2, also known as IL2. Levels of IL2 are low in the brain compared to the rest of the body as it can’t pass the blood-brain barrier. Together the team devised a new therapeutic approach that allows more IL2 to be made by brain cells, thereby creating the conditions needed by regulatory T cells to survive. A ‘gene delivery’ system based on an engineered adeno-associated viral vector (AAV) was used: this system can actually cross an intact blood brain barrier and deliver the DNA needed for the brain to produce more IL2 production. [Retrieved from https://neurosciencenews.com/tbi-immune-system-20671/].
Thymus (12th chakra and all chakras, high heart & mind, inward man)-Upper or Higher Heart Chakra (*aka God Unity Chakra, Ascension Chakra, Vagus Nerve Chakra). It is the “one” umpire known as the mind. Thymus- to be, have, belong, remain, imagine living in love (wisdom, curiosity, “intellect”, connect)-It is known as “the seat of the soul”, and our Higher Intelligence & Imagination or “The Mind”- for the fact that it: holds a record of traumatic or painful events, dimensional to the subliminal content (see intelligence model below) and ancestral narration (see imagination). High Heart Chakra, also called the ascended heart chakra, is connected with an organ: the thymus gland which before birth and throughout childhood (largest in the teen years-dormant at 50 years old). The thymus is a specialized primary lymphoid organ of the immune system. Within the thymus, thymus cell lymphocytes or T cells mature. T cells are critical to the adaptive immune system (also see RAS-GUT), where the body adapts specifically to foreign invaders. The thymus is located in the upper front part of the chest, in the anterior superior mediastinum, behind the sternum, and in front of the heart. It is made up of two lobes, each consisting of a central medulla and an outer cortex, surrounded by a capsule. [2] The thymus is instrumental in the production and maturation of T-lymphocytes or T cells, a specific type of white blood cell that protects the body from certain threats, including viruses and infections; It plays a role in immunity, autoimmunity, and aging (it’s basically our twin flame and fountain of youth). It’s made up of a scheme showing development of branchial epithelial bodies from the thoracic cavity of the foetus. I, II, III, IV. Branchial pouches. [4] The human leukocyte antigen (HLA) system or complex is a complex of genes on chromosome 6 in humans which encode cell-surface proteins responsible for the regulation of the immune system.[1] The HLA system is also known as the human version of the major histocompatibility complex (MHC) found in many animals.[2] More importanmtly, the “soul that is the seat of the mind”. [Retrieved from https://www.hindawi.com/journals/jtrans/2012/842141/; https://www.unseenwarfare.net/3-powers-of-the-soul; https://www.science.org/doi/10.1126/scisignal.abc8579; https://en.wikipedia.org/wiki/Thymus].
The Monad and the Permanent Seed Atom are different parts of the same functioning spirit body. When the seed atom is coming online the Monadic light generates into the diamond blueprint Diamond Heart filter of the permanent seed atom. The inner Monadic spirit ignites with the Mother’s Holy Spirit or the Amoraea Flame. The activated ‘Christ’ Seed Atom generates the instruction set of the Silicate Matrix and is the Universal Christos Field or 12D Ray. [Retrieved from https://ascensionglossary.com/index.php/Monad].
The Thymus and High Heart & Gut Relation
See Kidneys, See THYMUS (high heart), See Blood PH LEVELS: adrenal glands, also known as suprarenal glands, are small, triangular-shaped glands located on top of both kidneys here : The Spirit body of the Monad is only consciously aware of the contents of the Soul when it is connected to the Soul. This is the same as when the physical body is disconnected from the Soul, the conscious mind does not remember her (cannot feel the soul). When our Heart is healed, there is a fire that is ignited inside the Heart that is accessed, and the fire in the Heart is also in the Kidneys. There is a triangle that connects the Heart into the Kidneys. The Kidneys are in the base of the triangle from left to right and the point of the triangle is in the Heart. When the Heart is healed, there is a twin flame ignition in our Heart and Kidneys, which shifts the Heart configuration. Twin flames equals structure of light within the Heart. So two flames ignite in the Heart. The Monad is the greater flame and the physical body is the lesser flame. When this dual flame is ignited, there is an ignition in the Heart and a fire coming into the Kidneys, which is about blood cleansing. [Retrieved from https://ascensionglossary.com/index.php/Monad].
“And he who searches our hearts knows the mind of the Spirit, because the Spirit intercedes for God’s people in accordance with the will of God.” Romans 8:27 Retrieved from https://www.bible.com/en-GB/bible/111/ROM.8.27.NIV
24 – Retrieved from http://www.mcblab.net/lecture/20132-/chapter-15.pdf
Thymus Ancient Extracellular Signaling Molecule Matrix (ECM)
The thymus includes ancient extracellular signalling molecules which are cues, such as growth factors, hormones, cytokines, extracellular matrix components and neurotransmitters, designed to transmit specific information to target cells. Increasing knowledge about the roles of extracellular matrix and its components in the nervous system development and disease is important from the therapeutic viewpoint. Activation of signaling cascades underlying reorganization of the extracellular matrix and stimulation of neuronal plasticity is an achievable goal and a promising approach for treatment of acute and chronic neurodegenerative disorders. Recent data suggest that extracellular matrix proteases modifying cell recognition molecules on the neuronal surface, modulate synaptogenesis and plasticity during development and neurorepair. [Retrieved from https://www.frontiersin.org/research-topics/21996/extracellular-matrix-in-development-and-disorders-of-the-nervous-system; https://febs.onlinelibrary.wiley.com/doi/10.1111/febs.15776].
A new study reveals how adipocytes, or fat cells, play a role in cognitive decline and increased neurodegeneration risks. Using genetically modified mouse models, researchers found oxidative stress through exposure to a Western diet increased the production of inflammatory cytokines confined to adipocytes and altered protein markers of memory and cognition in the hippocampus. [Retrieved from https://neurosciencenews-com.cdn.ampproject.org/c/s/neurosciencenews.com/fat-cells-cognition-19521/amp/?fbclid=IwAR0EsMm7hYb1k-f63z0CfVd5cLiHRJ_RNavyXvI4U-0Jow03LuqA3EueXpQ].
As well, sympathetic [Anger] innervation of the thymus originates from the superior cervical and stellate ganglion. These fibers travel in a plexus along large blood vessels until they enter the thymic capsule. Parasympathetic fibers [Shame] arise from the vagus, recurrent laryngeal, and phrenic nerves. Several rodent studies have found that thymocytes respond to stimuli via norepinephrine, dopamine, acetylcholine, neuropeptide Y, vasoactive intestinal peptide, calcitonin gene-related peptide, and substance P.[2][6][2] [Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK539748/].
Research on the molecular and cellular basis of learning and memory has focused on the mechanisms that underlie the induction and expression of synaptic plasticity. There is increasing evidence that structural changes at the synapse are associated with synaptic plasticity and that extracellular matrix (ECM) components and cell adhesion molecules are associated with these changes (Retrieved from HERE).
“May our Lord Jesus Christ himself and God our Father, who loved us and by his grace gave us eternal encouragement and good hope, encourage your hearts and strengthen you in every good deed and word.”
2 Thessalonians 2:16-17 https://www2.bible.com/bible/111/2TH.2.16-17
The Thymus aka Leb, Lebab Cont.
The leb is “:The Veil”, of the five senses, also what enters the body, and absolutely essential for physical life and health, so too a healthy spiritual heart (mind (intellect), emotion (imagination), will (“ego”-good/love & bad/fear)) is at the center of one’s inner being (soul) is vital for a healthy soul, serving as the “fountain” of all moral attitudes and actions. The invisible realm of the spirit is as real as the visible world. In fact, the Scripture tells us that it is even more real (Hebrews 11:3). And just as God gave us five natural senses to interact with the physical world, He gave us five spiritual senses to connect with the supernatural world. The Leb- high heart, mind and “the gut” which is the bodily organ by means of which the raw data of experience is shaped into thoughts, concepts, or judgments. https://www.preceptaustin.org/heart_leb?fbclid=IwAR3sxBfseZ2LTzssTfOghYI_kfM-mtglVqyEqG3W7xAPJIQt3uODG9GjNdk
The puritan, John Flavel said, it’s light of the understanding, recognitions of the memory, seat of principles and the fountain of actions. John MacArthur – The “heart” commonly refers to the mind as the center of thinking and reason (Pr 3:3; 6:21;7:3), but also includes the emotions (Pr 15:15, 30), the will (Pr 11:20; 14:14), and thus, the whole inner being (Pr 3:5). The leb aka heart and mind carries along several other organs of the body (cf. ear and eyes already in Pr 4:20, 21) mentioned frequently in wisdom instruction: mouth, lips, and eyes (parallel to “eyelids” or “orbs” in Pr 4:25), mouth, lips, and even the foot and hand. The heart is the depository of all wisdom and the source of whatever affects speech (Pr 4:24), sight (Pr 4:25), and conduct (Pr 4:26, 27).
“Our mind [“leb”] receives information that it turns into emotional thoughts that act as a blueprint for shaping our material body, both inwardly and outwardly. We literally become what we think and imagine.” Retrieved from https://medcraveonline.com/MOJPB/dna-the-phantom-effect-quantum-hologram-and-the-etheric-body.html?fbclid=IwAR199BUqYjWCvNGq2GCgdzl3d0n_lVzu_6na4KVVcYVuBzk-JeiM-CgRyDQ
Our Euphraino, “the flexible mind”, relies the veil on The Truth in The gospel lies in your belief in Jesus’ coming to earth…please read below and think about how our subjective, discriminative knowledge and wisdom leads to understanding everything in terms of the following:
His Intention (Salvation- All Children of God):
- Awareness
- Knowledge
Our Own Revelation- “listening heart”
- Wisdom
His Affirmation (Unity- “The Chosen”, Sons of God)
- Understanding
Learn More HERE
He makes them listen to correction and commands…https://www.bible.com/en-GB/bible/111/JOB.36.10.NIV. In the past God overlooked such ignorance, but now he commands all people…
Note: The thymus (thymus chakra) brings Intelligence (God’s Affirmation- “mental acuteness”) and Imagination (God’s Intention- “perceived reality”) to balance to form our own Beliefs (Will)- it’s ultimately the convergence of knowledge and wisdom to gain a better understanding of everything!!! Read here how: https://wp.me/pbJRHH-15A
Peace I leave with you; my peace I give you. I do not give to you as the world gives. Do not let your hearts be troubled and do not be afraid. John 14:27 https://www.bible.com/en-GB/bible/111/JHN.14.27.NIV
ARAS (“The PERFECT” LEB- Lowly and Child-like) THE NARROW GATE PLUS BREATHING & BLOOD’S PH LEVELS
AGAIN, What is meekness? Being “Out of Darkness” and Overtaken, Upon The Presence Of His Light
ARAS (Super Conscious, Crown, Tippy TOP of Head, Child-Like BLISS to Live, Laugh, & Love=Perceiving Heaven ON Earth)
ARAS- (Woe To Meekness, No Longer Sloth or Spiritual Apathy) understand and fear [awe of Love”] of the Lord [“…with behavior that is a credit to the summons to God’s service, living as becomes you] with complete lowliness [in heart]: of mind (humility) and meekness (unselfishness, gentleness, mildness), with patience, bearing with one another and making allowances because you love one another. Ephesians 4:2 AMPC Note: Meekness is an attribute of human nature and behavior that has been defined as an amalgam [a mixture or blend “a curious amalgam of the traditional (OT) and the modern (NT)”] of righteousness, inner humility, and patience. Meekness is essentially an attitude or quality of heart whereby a person is willing to accept and submit without resistance to the will and desire of someone else. [Retrieved from https://www.regent.edu/journal/inner-resources-for-leaders/spiritual-meekness-a-virtue-for-christian-leaders/]. Take My yoke upon you and learn of Me, for I am gentle (meek) and humble (lowly) in heart, and you will find rest (relief and ease and refreshment and recreation and blessed quiet) for your souls. [Jer. 6:16.] Matthew 11:29 AMPC Lowliness of heart and mind are indispensable in our approach to our Heavenly Father and our hope of receiving revelation and sanctification. “Let nothing be done through strife or vainglory; but in lowliness of mind let each esteem other better than themselves” (Philippians 2:3). AND [Jesus] said to His disciples, Temptations (snares, traps set to entice to sin) are sure to come, but woe to him by or through whom they come! Luke 17:1 AMPC Rejoice and exult in hope; be steadfast and patient in suffering and tribulation; be constant in prayer. Romans 12:12 AMPC
Live, Laugh, & Love=Perceiving Heaven ON Earth (His “WORKS”- The Creator and Finisher)
I SEE SELF-CONTROL, PATIENCE, GENTLENESS, JOY< DIVINE LOVE
I HEAR KINDNESS, GOODNESS, PEACE <DIVINE HONOR
I KNOW THE LORD, IN HIS ALMIGHTY SPLENDOR
c. Divine Majesty- releases Sovereignty, The Advocate (1) to become The Perfect Three-One Harmony (The Light of Life)
(8, 9, 1) High Priesthood of Jesus & Now we are being in Divine Consecration- Prepared/Set Apart= being “yoked”/corded to His mutual affection with Holy Love [Divine Majesty]; Therefore, perceives as He does aka “The Leb” which Carries Us by Faith In Hope [Divine Love], Right Hand of Grace with The Fruit of The Spirit [Divine Honor], including His Godly aspects and attributes such as MEEKNESS and Virtue of love, peace, justice, selfless, mild, gentle. It is described in the Super conscious as being “The Rock“, and Strength of The “Oak Tree”, Gleam, Live Simple Truth, Observation of The Promises You Won (Victory), Protection, Serenity, Illuminati, The Halo who is friend always, advisor, & anchor. (ex. peace-loving, loving-kindness), & Appreciate Everything.
Breathing is a vital behavior that is particularly amenable to experimental investigation. We review recent progress on three problems of broad interest. (i) Where and how is respiratory rhythm generated? The preBötzinger Complex is a critical site, whereas pacemaker neurons may not be essential. The possibility that coupled oscillators are involved is considered. (ii) What are the mechanisms that underlie the plasticity necessary for adaptive changes in breathing? Serotonin-dependent long-term facilitation following intermittent hypoxia is an important example of such plasticity, and a model that can account for this adaptive behavior is discussed. (iii) Where and how are the regulated variables CO2 and pH sensed? These sensors are essential if breathing is to be appropriate for metabolism. Neurons with appropriate chemosensitivity are spread throughout the brainstem; their individual properties and collective role are just beginning to be understood. [Retrieved from https://www.annualreviews.org/doi/abs/10.1146/annurev.neuro.26.041002.131103].
Read More HERE
Prayer & BREATHING DAILY
FERVENT PRAYER (Fervent, Fervently) A — 1: ἐκτενής (Strong’s #1618 — Adjective — ektenes — ek-ten-ace’ ) denotes “strained, stretched” (ek, “out,” teino, “to stretch”); hence, metaphorically, “fervent,” 1 Peter 4:8 . Some mss. have it in Acts 12:5 , for the adverb (see B). Cp. ekteneia (with en), “intently, strenuously,” in Acts 26:7 , AV, “instantly,” RV, “earnestly.” Cp.
EARNEST. B — 1: ἐκτενῶς (Strong’s #1619 — Adverb — ektenos — ek-ten-oce’ ) “fervently”
(akin to A), is said of love, in 1 Peter 1:22; of prayer, in some mss. Acts 12:5 (see under A); for the comparative degree in Luke 22:44 , see EARNESTLY. C — 1: ζέω (Strong’s #2204 — Verb — zeo — dzeh’-o ) “to be hot, to boil” (Eng. “zeal” is akin), is metaphorically used of “fervency” of spirit, Acts 18:25; Romans 12:11 . Notes: (1) In Colossians 4:12 , the verb agonizomai, “to strive,” is translated “laboring fervently,” AV (RV, “striving”). (2) In 2 Corinthians 7:7 , the noun zelos, “zeal” (akin to C.), is translated “fervent mind,” AV (RV, “zeal”). (3) In James 5:17 , “he prayed fervently” (AV, “earnestly”) translates the noun proseuche, followed by the corresponding verb, lit., “he prayed with prayer.” In James 5:16 deesis, “supplication,” is so translated in the RV, for the AV, “effectual fervent prayer.” There is nothing in the original corresponding to the word “effectual.” The phrase, including the verb energeomai, “to work in,” is, lit., “the inworking supplication,” suggesting a supplication consistent with inward conformity to the mind of God. (4) For “fervent heat” see HEAT , B. A — 1: ἐνεργής (Strong’s #1756 —
- Adjective — energes — en-er-gace’ ) denotes “active, powerful in action” (en, “in,” ergon,
- “work;” Eng. “energy;” the word “work” is derived from the same root). It is translated
- “effectual” in 1 Corinthians 16:9 , of the door opened for the Gospel in Ephesus, and made
- “effectual” in the results of entering it; and in Philemon 1:6 , of the fellowship of Philemon’s faith “in the knowledge of every good thing” (RV). In Hebrews 4:12 it describes the Word of God as “active,” RV (AV, “powerful”), i.e., full of power to achieve results. See ACTIVE , POWERFUL.
EFFECTUAL PRAYER B — 1: ἐνεργέω (Strong’s #1754 — Verb — energeo — en-erg-eh’-o ) “to put forth power, be operative, to work” (its usual meaning), is rendered by the verb “to work effectually,” or “to be effectual,” in the AV of 2 Corinthians 1:6; Galatians 2:8; 1 Thessalonians 2:13; in each case the RV translates it by the simple verb “to work” (past tense, “wrought”). In James 5:16 the RV omits the superfluous word “effectual,” and translates the sentence “the supplication of a righteous man availeth much in its working,” the verb being in the present participial form. Here the meaning may be “in its inworking,” i.e., in the effect produced in the praying man, bringing him into line with the will of God, as in the case of Elijah. For a fuller treatment of the word, see WORK. See also DO , MIGHTY , SHEW , Note (11).
Note: The noun energeia, “working,” is translated “effectual working,” in the AV of Ephesians 3:7; 4:16 See gnēsiōs- gnay-SEE-ose [Pure Heart] “sincerely, honorably” (akin to A, No. 3), is rendered “truly” (marg., “genuinely”) in Phil, 2:20 (AV, “naturally”). Read More HERE* see image below The Trinity- US< GOD, UNIVERSE<LOVE= THREE IN ONE Show (sight) & Tells You (hear) IN WORD ABOUT The Future So Pray; Prayer and contemplation
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Who are considered the Neurodiverse?
What is neurodiversity? Individual differences in brain functioning regarded as normal variations within the human population because of genes, environmental, and intersecting factors. Intersecting identities is the concept that an individual’s identity consists of multiple, intersecting factors, including but not limited to gender identity, gender expression, race, ethnicity, class (past and present), religious beliefs, sexual identity and sexual expression. [Retrieved from https://en.wikipedia.org/wiki/Intersectionality].
Developmental
Developmental Coordination Disorder (DCD)
Dyspraxia
Developmental Language Disorder (DLD)
Dyscalculia
Benign Rolandic Epilepsy (BRE)
Dyslexia
Autism Spectrum Condition (ASC)
Fetal Alcohol Syndrome (FASD)
Attention Hyperactivity Disorder (ADHD)
Visual Impairment (VI)
Chronic Fatigue Syndrome (CFS)
Physical/Mental
Hearing/Vision Impairment (HI)
Tic Disorders
Joint Hypermobility Syndrome (JHS)
Depression
Post Traumatic Stress Disorder (PSTD)
Anxiety Disorder
Borderline Personality Disorder (BPD)
Bipolar Disorder (BD)
Obsessive Compulsive Disorder (OCD)
Schizophrenia
Acquired
Migraines
Epilepsy
Traumatic Brain Injury (TBI)
Parkinsons
Huntingdons Chorea
Dementia
Motor Neuron Disease (MND)
Cerebral Vascular Accident (CVA)
Learn more:
- Childhood trauma
- Dissemination Evidence-based treatment
- Learning collaborative
- Calm & Listening Skills
- Trainings on Neurodevelopmental Disorders (NDDs): Neurodiverity in Auditory Processing; Neurodevelopmental Disorders (NDDs): Neurodiverity in Visual Processing; Dysphonetic “Auditory” Dyslexia; Dyseidetic “Visual-Surface” Dyslexia; Directional “Geographic-Spacial” Dyslexia; Dysphoneidetic “Mixed” Dyslexia; Developmental Dyslexia; Acquired Dyslexia Stealth Dyslexia; Gifted & Talented; (2E) Twice Exceptionality; (ADHD-Any of the 3 types) Attention-Deficit Disorder; (SPD) Sensory Processing Disorder; (IDD) Interoceptive Discrimination Disorder (DCD) Developmental Coordination Disorder; (SLI) Specific Language Impairment (DLD); Developmental Language Disorder *sounds and language; Irlen Syndrome; (APD) Auditory Processing Disorder such as Central Processing Disorder C(APD); (ASD/ASC) Autism Spectrum Disorder (VPD); Visual Processing Disorder such as Convergence Insufficiency (CI); (LD) Learning Disability General Processing Disorder (see terms above) such as Hearing Loss/Impaired= those who use the term “hard of hearing“ (ID) Intellectual Disability (GDD) Global Developmental Delay; (TBI) Traumatic Brain Injury; Personality Disorder such as Narcism Behavioral Disorder such as ODD Obedient Defiant Disorder; Executive Functioning Problems or Disorder; OCD, Anxiety, & Depression; Schizophrenia (SZ) Epileptic Encephalopathies (EE)
Evidence-based mental health interventions for traumatized youth: A st… https://www.sciencedirect.com/science/article/pii/S0005796711001367
THE AUDITORY BRAINSTEM RESPONSE (ABR) & MEASURES OF PH IN THE BLOOD: EVALUATES RISK FACTORS FOR HEARING LOSS. This (1980) found fourteen of 100 unselected patients in an Intensive care nursery were found by the auditory brainstem evoked response (ABR) method to suffer significant hearing loss; of these 8 were ultimately discharged home. Analysis of the 100 clinical records identified 9 risk factors of which most, like low Apgar scores, are already known (Table I). However, neonatal asphyxia appeared to be associated with hearing loss only when repeated episodes of acidosis accompanied it (Table III). We conclude that the ABR readily identifies the hard-of-hearing premature and estimates the type and amount of his peripheral hearing loss, and that physiological events associated with prolonged perfusion of the cochlea with blood low in pH may be the most common cause of hearing disorder in this group. [Retrieved from https://www.nature.com/articles/pr198036].
What makes a PH level to be considered healthy? Think about other diversities? See THYMUS (high heart)-ARAS (thymus, pons, RAS/HPA & ACC): adrenal glands, also known as suprarenal glands, are small, triangular-shaped glands located on top of both kidneys.
A normal blood pH level is 7.35 to 7.45 on a scale of 0 to 14, where 0 is the most acidic and 14 is the most basic. This value can vary slightly in either direction. If the lungs or kidneys are malfunctioning, your blood’s pH level can become imbalanced. Intracellular pH (pHi) regulation in the brain is important in both physiological and physiopathological conditions because changes in pHi generally result in altered neuronal excitability. In this review, we will cover 4 major areas: (1) The effect of pHi on cellular processes in the brain, including channel activity and neuronal excitability. (2) pHi homeostasis and how it is determined by the balance between rates of acid loading (JL) and extrusion (JE). The balance between JE and JL determine steady-state pHi, as well as the ability of the cell to defend pHi in the face of extracellular acid-base disturbances (e.g., metabolic acidosis). (3) The properties and importance of members of the SLC4 and SLC9 families of acid-base transporters expressed in the brain that contribute to JL (namely the Cl-HCO3 exchanger AE3) and JE (the Na-H exchangers NHE1, NHE3, and NHE5 as well as the Na+- coupled HCO3− transporters NBCe1, NBCn1, NDCBE, and NBCn2). (4) The effect of acid-base disturbances on neuronal function and the roles of acid-base transporters in defending neuronal pHi under physiopathologic conditions. [Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923155/].
Retrieved from https://www.achieveability.org.uk/files/1460064713/neurodiversity-with-reference-to-dyspraxia-mary-colly.pdf; American Psychiatric Association (1994) DSM-IV-TR Diagnostic and Statistical Manual of Mental Disorders. Washington DC, APA, https://www.psychiatry.org/patients-families.
Note: With Neurodevelopmental Disorders (NDDs), comes neurodivergency, you use inductive reasoning to solve problems, which is a cause-and-effect type of thinking, where someone begins identifying patterns by empirical observations of feelings and the future applications Neuodivergency means having an induction logic versus deduction like a vast majority of people. With this being said, disparagement can happen and cause trauma. Disparagement can be soul crushing!
Specific Leaning Disability (SLD) “An estimated 80 percent of those with learning disorders have reading disorder in particular (commonly referred to as dyslexia). One-third of people with learning disabilities are estimated to also have attention-deficit hyperactivity disorder (ADHD).”
Retrieved from https://www.psychiatry.org/patients-families/specific-learning-disorder.
Autism Spectrum Condition (ASC) ” Exogenous prenatal risks are evident (e.g. valproate and toxic chemicals) or possible (e.g. selective serotonin reuptake inhibitors), and processes endogenous to the materno-foeto-placental unit (e.g. maternal diabetes, enhanced steroidogenic activities and maternal immune activation) likely heighten offspring vulnerability to ASC.” [Retrieved from https://acamh.onlinelibrary.wiley.com/doi/abs/10.1111/jcpp.12501].
Other
Seasonal Affective Disorder (SAD) include fatigue, even with too much sleep, and weight gain associated with overeating and carbohydrate cravings. SAD may begin at any age, but it typically starts when a person is between ages 18 and 30. SAD symptoms can vary from mild to severe and can include many symptoms similar to major. [See here-
Retrieved from https://www.psychiatry.org/patients-families/depression/seasonal-affective-disorder].
PTSD- Many advances in science have been made in the last decade to better explain the pathogenesis of PTSD. Advances in the brain imaging method have allowed us to study changes in patients’ brains in a non-invasive way. Recent studies have observed the activity or morphology changes of several brain regions in patients with PTSD, including the prefrontal lobe, amygdala, hippocampus. However, it is still unclear how these changes in brain regions are linked to PTSD. Further research needs to be conducted to understand the function of brain regions during the development of PTSD. Also, people can develop PTSD, depression, or both as a result of a major traumatic event. The hypothalamic–pituitary–adrenal axis (HPA axis) may play an important role in such a difference (see HPA and anger above). [Retrieved from https://www.frontiersin.org/research-topics/21025/comprehensive-understanding-of-ptsd-from-pathogenesis-to-intervention].
Pathological Demand Avoidance of PDA is becoming more widely recognized as a distinct profile of autism. British psychologist Elizabeth Newson came up with this term which describes an anxiety-driven need to be in control and avoid other people’s demands and expectations. Demand avoidance in the PDA profile looks different from what others on the autism spectrum experience because of its extreme nature and obsessive quality. Research done at the University of Newcastle in November 2016 found that Intolerance of Uncertainty (IU) was also associated with PDA, in fact even stronger than anxiety. [Retrieved from https://autismawarenesscentre.com/an-introduction-to-pathological-demand-avoidance-pda/?fbclid=IwAR3wuIGRCU3nViiYIxbqAHj0zKhPvWERF7y536oUXy5lIXan17ZOD1soaYc].
For many people, a traumatic experience can leave an indelible impression on the brain in the form of post-traumatic stress disorder (PTSD). PTSD is characterized by hyperarousal and avoidance of risky, potentially aversive behaviors. [Retrieved from https://neurosciencenews.com/ptsd-valence-system-19569/].
Deficient emotional self-regulation (DESR) is a relatively new term used to describe the problem of impulsive emotion coupled with emotional self-regulation difficulties — issues long associated with attention deficit hyperactivity disorder (ADHD or ADD). DESR may be new to the ADHD lexicon, however I argue that it is a core and commonly overlooked component of the disorder — and one that can help predict a patient’s impairments, and even improve diagnostic and treatment practices.1
Dysthymia- People with untreated ADHD can suffer from dysthymia — a mild but long-term mood disorder or sadness. It is often brought on by living with the frustrations, failures, negative feedback, and stresses of life due to untreated or inadequately treated ADHD. People who are dysthymic suffer almost every day from low energy and self-esteem. [Retrieved from https://www.additudemag.com/slideshows/adhd-emotions-understanding-intense-feelings/‘].
Borderline Personality Disorder (BPD)- What is also interesting is that ‘child maltreatment and efficiency of the conflict attention (Alerting, Orienting, and Executive Function Networks) and their interactions of the networks along with their independently predicted scores on the (BPD) precursors composite. Maltreated children had higher mean scores on the BPD precursors composite, and children classified as having high levels of these precursors were more prevalent in the maltreatment group.’ Development and Psychopathology Volume 17, Issue 4, December 2005, pp. 1071 – 1089 DOI: https://doi.org/10.1017/S0954579405050509.
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Humbled by His Faith, for: “You will need to position yourself for a breakthrough. Quit pondering the past. In other words, stop dwelling on your past failures and those things that just didn’t seem to go right for you [personal/other expectations- guilt]. “Chronicles 20:17.
A study of human brain tissue suggests clinical depression reduces the quantity of astrocyte cells in key regions
Depression (major depressive disorder) is a common and serious medical illness that negatively affects how you feel, the way you think and how you act. Fortunately, it is also treatable. Depression causes feelings of sadness and/or a loss of interest in activities once enjoyed. It can lead to a variety of emotional and physical problems and can decrease a person’s ability to function at work and at home. [Retrieved from https://www.psychiatry.org/patients-families/depression]
In another study, they studied how loneliness is correlated with a higher risk of developing mental conditions. They studied how deterioration can occur in physical health, and is linked to mortality and higher health care utilizationa combination of personality traits and childhood circumstances account for why some older people experience loneliness more than others. Lonely adults over 50 were 1.24 times more likely to have rarely, or never, had comfortable friendships during childhood, and 1.34 times more likely to have had poor relationships with their mothers as children [think about impacts of learning with trauma…Retrieved from https://neurosciencenews.com/childhood-personality-loneliness-20606/].
In a present study, “The researchers were particularly interested in three brain regions, the dorsomedial prefrontal cortex (see Ras- HPA), dorsal caudate nucleus and mediodorsal thalamus (see Ras- ACC), which have been implicated in depression (see Pons).” (*see mainly HPA-anger/ACC-shame related to RAS in section above related to Pons and Thymus) Retrieved from https://www.psypost.org/2021/05/new-study-of-human-brain-tissue-suggests-clinical-depression-reduces-the-quantity-of-astrocyte-cells-in-key-regions-60668 by Eric W. Dolan; May 4, 2021in Cognitive Science, Depression.
25 – dorsomedial prefrontal cortex controlled subconsciously by HPA (anger)
26 – dorsal caudate nucleus controlled subconsciously by ACC (shame)
27 – mediodorsal thalamus controlled subconsciously by PONS (anger/shame)
The gut microbiota forms part of a complex network termed the microbiota-gut-brain axis along with the enteric nervous system, sympathetic and parasympathetic divisions of the autonomic nervous system, neuroendocrine and neuroimmune components the central nervous system. The gut microbiota is associated with…The gut microbiota forms part of a complex network termed the microbiota-gut-brain axis along with the enteric nervous system, sympathetic and parasympathetic divisions of the autonomic nervous system, neuroendocrine and neuroimmune components the central nervous system. The gut microbiota is associated with neuropsychiatric disorder such as schizophrenia, autistic disorders, anxiety disorders, major depression and bipolar disorder. Major depressive disorder is a stress-related mood disorder associated with a disrupted HPA axis, and evidence suggests that the gut microbiota play a key role in modulating depression. Bipolar disorder is a severe psychiatric disorder with dysfunctions of neuroimmune system which also suggest the brain-gut-microbiota axis is an important physiological mechanism. (See Dysautonomia, HPA and anger above).
Communication from gut to brain occurs through tryptophan, an essential building block of serotonin. Serotonin is key in regulating mood, eating, and sleep patterns. There is limited storage capacity for tryptophan in the brain, and a constant supply is required from the gut. It was once believed that tryptophan came strictly from diet alone, but what research has shown is that gut microbiota, particularly Bifidobacterium, produces tryptophan and increases its levels in the bloodstream. This study below has since been replicated, adding to global evidence linking the microbiome-gut-brain axis to stress and mental health disorders. Low diversity in the gut microbiota is now considered a significant biomarker for major depressive disorder. Other mental health and neurodegenerative disorders with significant microbiome-gut-brain ties include: post-traumatic stress disorder, bipolar disorder, schizophrenia, Parkinson’s disease, and autism. The microbiome-gut-brain axis also plays a critical role in irritable bowel syndrome, and in understanding the link between mental health disorders and physical illness, such as depression or anxiety co-occurring with inflammatory bowel disease. (Retrieved from https://trauma.blog.yorku.ca/2021/10/what-gut-bacteria-can-teach-us-about-mental-illness/?fbclid=IwAR0v5JnnKUkwHyd3vFTYulwq_tWc-jje5uO9jB7JShBQiNAwVdeidSw4rUM].
Lastly, potential mechanism include changes in microbial content, immune stimulation, neural pathways (via the vagus nerve), tryptophan metabolism, gut hormonal response, and bacterial metabolites.
Retrieved from https://www.frontiersin.org/research-topics/7323/involvement-of-neuro-immune-mechanism-and-brain-gut-axis-in-pathophysiology-of-mood-disorders
Other NDD’s
Most people are unaware of the connection between dyslexia and ADD or ADHD. It has been estimated that between 30 – 60% of kids with dyslexia also have either ADD or ADHD.
“Challenges with processing emotions start in the brain itself. Sometimes the working memory impairments of ADHD allow a momentary emotion to become too strong, flooding the brain with one intense emotion.” Thomas Brown, Ph.D.
Brain imaging studies demonstrate that chemicals that activate reward-recognizing circuits in the brain tend to bind on significantly fewer receptor sites in people with ADHD than do those in a comparison group. People with ADHD are less able to anticipate pleasure or register satisfaction with tasks for which the payoff is delayed.
Few doctors factor in emotional challenges when making an ADHD diagnosis. In fact, current diagnostic criteria for ADHD include no mention of “problems with emotions.” At other times, working memory impairments leave the person with insufficient sensitivity to the importance of a particular emotion because he or she hasn’t kept other relevant information in mind. Challenges with emotions start in the brain itself. Sometimes the working memory impairments of ADHD allow a momentary emotion to become too strong, flooding the brain with one intense emotion [emotional intensity or insensitivity]. At other times, the person with ADHD seems insensitive or unaware of the emotions of others. Brain connectivity networks carrying information related to emotion seem to be somewhat more limited in individuals with ADHD.
Gifted & Talented Plus 2e
The term “twice-exceptional,” also referred to as “2e,” is used to describe gifted children who, have the characteristics of gifted students with the potential for high achievement and give evidence of one or more disabilities as defined by federal or state eligibility criteria. These disabilities may include specific learning disabilities (SpLD), speech and language disorders, emotional/behavioral disorders, physical disabilities, autism spectrum, or other impairments such as attention deficit hyperactivity disorder (ADHD) [Retrieved from https://www.nagc.org/resources-publications/resources-parents/twice-exceptional-students.
Emotional Intensity (see pons above and insensitive below)- It is characterized by heightened and intense feelings, a constant stream of both positive and negative feelings – pain, distress, despair, fear, excitement, love, sadness or happiness – sometimes a mixture of many at the same time; For my program, it’s mainly: anger, shame, happiness (joy), grief, courage (might), and harmony!
Emotionally overexcitable (OE) is often the first to be noticed by parents. It is reflected in heightened, intense feelings, extremes of complex emotions, identification with others’ feelings, and strong affective expression (Piechowski, 1991). Other manifestations include physical responses like stomachaches and blushing or concern with death and depression (Piechowski, 1979). Emotionally overexcitable people have a remarkable capacity for deep relationships; they show strong emotional attachments to people, places, and things (Dabrowski & Piechowski, 1977). They have compassion, empathy, and sensitivity in relation-ships. Those with strong Emotional OE are acutely aware of their own feelings, of how they are growing and changing, and often carry on inner dialogs and practice self-judgment (Piechowski, 1979, 1991). Children high in Emotional OE‚ are often accused of “overreacting.” Their compassion and concern for others, their focus on relationships, and the intensity of their feelings may interfere with everyday tasks like homework or doing the dishes. [Retrieved from https://www.sengifted.org/post/overexcitability-and-the-gifted].
Also- Dabrowski identified five areas of intensity-Psychomotor, Sensual [MORAL], Intellectual, Imaginational, and Emotional- please think of hyper-, hypo- and varied thymus as it relates to being balanced, regulated, calm and homeostasis can happen!!
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